A randomized controlled trial demonstrates the effectiveness of adjustments in relieving infantile colic.  One group of infants received adjustments for 2 weeks, the other was treated with the drug dimethicone for 2 weeks.  By trial days 4 to 7, the hours of crying were reduced by 1 hour in the dimethicone group compared with 2.4 hours in the group that was adjusted.  On days 8 to11, crying was reduced by 1 hour for the dimethicone group, whereas crying in the group that was adjusted was reduced by 2.7 hours.  From trial day 5 onward, the group that was adjusted showed significantly more improvement than the dimethicone group.  Wiberg JM, Nordsteen J, Nilsson N,  Journal of Manip Physiol Ther 1999 (Oct); 22(8): 517-522.

In a prospective study of 316 infants, researchers found that 94% of participants appeared to have positive changes within 14 days from the start of care.  The infants included in the study had moderate to severe infantile colic.  The researchers founds that chiropractic care resulted in both a reduction in the daily length of the colic periods and a reduction in the number of colic periods each day.  Klougart N,  Nilsson N, and Jacobsen J.  "Infantile Colic Treated by Chiropractors:  Prospective Study of 316 Cases."  Journ of Manipulative and Physiol Therap. 1998.